Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 3/20 | 0.47 |
| ▸ | CLK1 | P49759 | 7/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 4/20 | 0.41 |
| ▸ | CCNK | O75909 | 4/20 | 0.38 |
| ▸ | CDK12 | Q9NYV4 | 4/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.38 |
| ▸ | CDK2 | P24941 | 3/20 | 0.38 |
| ▸ | CDK9 | P50750 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 3/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.37 |
| ▸ | PRKACA | P17612 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15598335 | 0.85 | CCNK (0.43) | MAP3K14CCNKCDK12CCNT1CCNE1 | |
| SCHEMBL15565642 | 0.78 | CCNK (0.48) | CDK5CCNKCDK12CCNT1CCNE1 | |
| SCHEMBL15565644 | 0.78 | CCNK (0.48) | CDK5CCNKCDK12CCNT1CCNE1 | |
| SCHEMBL15598388 | 0.78 | CCNK (0.48) | CDK5CCNKCDK12CCNT1CCNE1 | |
| SCHEMBL24839617 | 0.75 | CLK1 (0.49) | MAP3K14CLK1CDK5CDK5R1CCNK | |
| SCHEMBL15564943 | 0.74 | CCNK (0.42) | MAP3K14CCNKCDK12CCNT1CCNE1 | |
| SCHEMBL15565491 | 0.70 | CCNK (0.43) | MAP3K14CCNKCDK12CCNT1CCNE1 | |
| SCHEMBL25029293 | 0.69 | MAP3K14 (0.48) | MAP3K14CCNKCDK12CCNT1CCNE1 | |
| SCHEMBL29364271 | 0.69 | MAP3K14 (0.48) | MAP3K14CCNKCDK12CCNT1CCNE1 | |
| SCHEMBL25600700 | 0.68 | CCNK (0.48) | MAP3K14CCNKCDK12CCNT1CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022079250-A1 | COMPOUNDS FOR THE TREATMENT OF VIRAL INFECTIONS | MERCK PATENT GMBH (DE) | 2022-04-21 | — | — | WO | disclosed |