SCHEMBL2431208

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2433595	0.93	GRM4 (0.36)	MAPTHTTGRM4RAB9ASMN1; SMN2
	SCHEMBL2429131	0.90	GRM4 (0.33)	KDM4EHTTATMGRM4
	SCHEMBL2433596	0.89	MAPT (0.36)	MAPTHTTGRM4RAB9ASMN1; SMN2
	SCHEMBL2432673	0.88	PTPN1 (0.46)	MAPTKDM4EHTTATMGRM4
	SCHEMBL2432670	0.88	PTPN1 (0.46)	MAPTKDM4EHTTATMGRM4
	SCHEMBL2435744	0.87	RAB9A (0.41)	MAPTKDM4EHTTATMGRM4
	SCHEMBL2435749	0.87	RAB9A (0.41)	MAPTKDM4EHTTATMGRM4
	SCHEMBL14042864	0.82	KDM4E (0.43)	MAPTKDM4EHTTATMRAB9A
	SCHEMBL2428555	0.82	GRM4 (0.31)	GRM4
	SCHEMBL4156654	0.80	KDM4E (0.53)	MAPTKDM4EHTTATMRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.