Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12896165 | 0.79 | HSD17B10 (0.37) | HSD17B10APP | |
| SCHEMBL2429093 | 0.76 | ACE2 (0.40) | — | |
| SCHEMBL2428391 | 0.73 | NOTUM (0.33) | HSD17B10 | |
| SCHEMBL2432377 | 0.71 | DRD2 (0.31) | — | |
| SCHEMBL2430281 | 0.69 | ESR1 (0.35) | — | |
| SCHEMBL17037102 | 0.69 | LIMK1 (0.36) | HSD17B10APP | |
| SCHEMBL19155499 | 0.68 | LIMK1 (0.42) | HSD17B10APP | |
| SCHEMBL13520159 | 0.67 | LIMK1 (0.44) | HSD17B10APP | |
| SCHEMBL12732588 | 0.67 | BCL2L1 (0.39) | — | |
| SCHEMBL19436248 | 0.65 | FFAR1 (0.47) | HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011109679-A2 | INHIBITORS OF 5-LIPOXYGENASE | AMIRA PHARMACEUTICALS, INC. (US) | 2011-09-09 | — | — | WO | disclosed |
| WO-2011109679-A2 | INHIBITORS OF 5-LIPOXYGENASE | AMIRA PHARMACEUTICALS, INC. (US) | 2011-09-09 | — | — | WO | disclosed |