Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2428391 | 0.95 | NOTUM (0.33) | NOTUM | |
| SCHEMBL12325837 | 0.81 | LOXL2 (0.34) | NOTUM | |
| SCHEMBL2431808 | 0.80 | — | — | |
| SCHEMBL2429181 | 0.73 | NOTUM (0.30) | NOTUM | |
| SCHEMBL2429322 | 0.73 | HSD17B10 (0.33) | — | |
| SCHEMBL12325635 | 0.72 | NOTUM (0.37) | NOTUM | |
| SCHEMBL2431221 | 0.71 | HSD17B10 (0.34) | — | |
| SCHEMBL2432379 | 0.71 | NOTUM (0.32) | NOTUM | |
| SCHEMBL2433157 | 0.69 | ESR1 (0.35) | — | |
| SCHEMBL2436473 | 0.68 | NPC1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011109679-A2 | INHIBITORS OF 5-LIPOXYGENASE | AMIRA PHARMACEUTICALS, INC. (US) | 2011-09-09 | — | — | WO | disclosed |
| WO-2011109679-A2 | INHIBITORS OF 5-LIPOXYGENASE | AMIRA PHARMACEUTICALS, INC. (US) | 2011-09-09 | — | — | WO | disclosed |