SCHEMBL2431228

SCHEMBL2431228

C=C(C=C(CC)C(=O)O)C(=O)OCC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.41
ALDH1A1 P00352 5/20 0.40
TSHR P16473 1/20 0.40
MAPT P10636 2/20 0.38
GLO1 Q04760 1/20 0.37
CYP2D6 P10635 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
SOAT1 P35610 1/20 0.35
THRB P10828 1/20 0.35
EGLN1 Q9GZT9 1/20 0.35
HCAR2 Q8TDS4 1/20 0.34
LMNA P02545 1/20 0.32
HSD17B10 Q99714 1/20 0.32
CYP2C9 P11712 1/20 0.32
GAA P10253 2/20 0.31
ALOX15 P16050 1/20 0.31
MGAM O43451 1/20 0.31
SI P14410 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylic Acid SCHEMBL10765376 0.93 NPSR1 (0.37) NPSR1ALDH1A1TSHRMAPTGLO1
SCHEMBL10904258 0.85 TSHR (0.39) NPSR1ALDH1A1TSHRMAPTTHRB
SCHEMBL1245379 0.83 ALDH1A1 (0.37) ALDH1A1TSHREGLN1
Methacrylic Acid SCHEMBL9147315 0.82 THRB (0.38) NPSR1ALDH1A1TSHRMAPTGLO1
Hydrochloric Acid SCHEMBL1562603 0.81 THRB (0.42) TSHRMAPTCYP2D6SMN1; SMN2THRB
SCHEMBL5595771 0.80 FFAR3 (0.35) ALDH1A1TSHR
SCHEMBL18169351 0.80 FFAR3 (0.35) ALDH1A1TSHR
SCHEMBL432150 0.79 NPSR1 (0.42) NPSR1ALDH1A1TSHRMAPTGLO1
SCHEMBL14406989 0.79 NPSR1 (0.45) NPSR1ALDH1A1TSHRMAPTGLO1
Ammonia Solution, Strong SCHEMBL15128898 0.78 NPSR1 (0.41) NPSR1ALDH1A1TSHRMAPTGLO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4121017-A1 EXPANDABLE, MULTI-EXCIPIENT STRUCTURED DOSAGE FORM FOR PROLONGED DRUG RELEASE Blaesi, Aron H. (CH) 2023-01-25 EP claimed
US-20220304924-A1 Expandable multi-excipient dosage form BLAESI, ARON H. (US) 2022-09-29 US claimed
WO-2021188742-A1 EXPANDABLE, MULTI-EXCIPIENT STRUCTURED DOSAGE FORM FOR PROLONGED DRUG RELEASE BLAESI ARON H (US) 2021-09-23 WO claimed
WO-2009067684-A1 MODIFIED RELEASE NIACIN FORMULATIONS CAPRICORN PHARMA INC. (US) 2009-05-28 WO claimed
US-20090130208-A1 Modified release niacin formulations CAPRICORN PHARMA INC. (US) 2009-05-21 US claimed
EP-4121017-A1 EXPANDABLE, MULTI-EXCIPIENT STRUCTURED DOSAGE FORM FOR PROLONGED DRUG RELEASE Blaesi, Aron H. (CH) 2023-01-25 EP disclosed
US-20220304924-A1 Expandable multi-excipient dosage form BLAESI, ARON H. (US) 2022-09-29 US disclosed
US-11357730-B2 Controlled activation ingestible identifier OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2022-06-14 US disclosed
WO-2021188742-A1 EXPANDABLE, MULTI-EXCIPIENT STRUCTURED DOSAGE FORM FOR PROLONGED DRUG RELEASE BLAESI ARON H (US) 2021-09-23 WO disclosed
CN-110269838-A Propane -1- sulfonic acid { 3- [5- (the chloro- phenyl of 4-) -1H- pyrrolo- [2,3-b] pyridine -3- carbonyl] -2,4- difluorophenyl }-amide compositions and application thereof 豪夫迈罗氏公司 2019-09-24 CN disclosed
US-20190133958-A1 CONTROLLED ACTIVATION INGESTIBLE IDENTIFIER OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2019-05-09 US disclosed
US-10238604-B2 Controlled activation ingestible identifier PROTEUS DIGITAL HEALTH, INC. (US) 2019-03-26 US disclosed
EP-1467207-A1 SCREENING METHOD Takeda Chemical Industries, Ltd. (JP) 2004-10-13 EP disclosed
EP-0954292-B1 PHARMACEUTICAL FORMULATIONS WITH DELAYED DRUG RELEASE POLICHEM SA (LU) 2003-07-02 EP disclosed
US-6190692-B1 Time-specific controlled release capsule formulations and method of preparing same BUSETTI CESARE (IT) 2001-02-20 US disclosed
EP-0954293-A1 TIME-SPECIFIC CONTROLLED RELEASE DOSAGE FORMULATIONS AND METHOD OF PREPARING SAME Polin Industria Chimica S.p.A. (IT) 1999-11-10 EP disclosed
US-5891474-A Time-specific controlled release dosage formulations and method of preparing same POLI INDUSTRIA CHIMICA, S.P.A. (IT) 1999-04-06 US disclosed
US-5788987-A TIME-SPECIFIC CONTROLLED RELEASE DOSAGE FORMULATION POLI INDUSTRIA CHIMICA SPA (IT) 1998-08-04 US disclosed
WO-1998032426-A1 TIME-SPECIFIC CONTROLLED RELEASE DOSAGE FORMULATIONS AND METHOD OF PREPARING SAME POLIN INDUSTRIA CHIMICA S.P.A. (IT) 1998-07-30 WO disclosed
CN-1179102-A 2-methyl-thieno-benzodiazepine * oral formulations LILLY CO ELI (US) 1998-04-15 CN disclosed