Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.46 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | ATR | Q13535 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.36 |
| ▸ | AOC1 | P19801 | 2/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.36 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.36 |
| ▸ | RAF1 | P04049 | 1/20 | 0.36 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.36 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.35 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29473296 | 0.98 | DPP4 (0.44) | DPP4EGFRCASP6MAPK14LOXL2 | |
| SCHEMBL27908490 | 0.85 | MAPK14 (0.37) | DPP4EGFRCASP6MAPK14CYP1A2 | |
| Hydrochloric Acid SCHEMBL29723641 | 0.85 | TAAR1 (0.39) | DPP4EGFRCASP6LOXL2 | |
| Hydrochloric Acid SCHEMBL23498194 | 0.85 | TAAR1 (0.39) | DPP4EGFRCASP6LOXL2 | |
| SCHEMBL28144739 | 0.82 | CASP6 (0.39) | EGFRCASP6MAPK14MAPK10CYP46A1 | |
| SCHEMBL24312483 | 0.82 | CYP2D6 (0.43) | EGFRCASP6CYP46A1CYP1A2CYP2D6 | |
| SCHEMBL7503631 | 0.82 | CASP6 (0.42) | EGFRCASP6MAPK14ATRCYP46A1 | |
| SCHEMBL10601314 | 0.80 | MAPK9 (0.43) | EGFRCASP6MAPK14MAPK10HSP90AA1 | |
| SCHEMBL3790206 | 0.79 | KDM4E (0.50) | DPP4LOXL2ATRHSP90AA1CYP1A2 | |
| SCHEMBL29496884 | 0.79 | KDM4E (0.50) | DPP4LOXL2ATRHSP90AA1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220119395-A1 | BICYCLIC COMPOUNDS | ALIGOS THERAPEUTICS, INC. | 2022-04-21 | — | — | US | disclosed |
| WO-2022081758-A1 | BICYCLIC COMPOUNDS | ALIGOS THERAPEUTICS, INC. (US) | 2022-04-21 | — | — | WO | disclosed |
| CN-103254241-B | Organometallic complex, light-emitting element, light-emitting device, electronic device and lighting device | SEMICONDUCTOR ENERGY LAB | 2015-06-17 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220119395-A1 | BICYCLIC COMPOUNDS | SLC10A1, PKD1, CYP11B2 | DPP4 651/4885EGFR 2452/4885CASP6 2981/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.