Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 4/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.32 |
| ▸ | VNN1 | O95497 | 2/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.31 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27813907 | 0.81 | PDK1 (0.43) | DPP4PDK1 | |
| SCHEMBL25075386 | 0.76 | HRH3 (0.37) | HRH3CYP2D6KCNH2 | |
| SCHEMBL19735103 | 0.75 | KDM4E (0.37) | PIK3CDDPP4CHRNB2CHRNA3CHRNA4 | |
| SCHEMBL7906643 | 0.75 | CHRNB2 (0.48) | PIK3CDCHRNB2CHRNA3CHRNA4CHRNB3 | |
| SCHEMBL23743935 | 0.74 | CHRNB2 (0.44) | PIK3CDDPP4VNN1CHRNB2CHRNA3 | |
| SCHEMBL24312690 | 0.74 | DPP4 (0.35) | PIK3CDDPP4PDK1 | |
| SCHEMBL22327875 | 0.74 | CHRNB2 (0.44) | PIK3CDDPP4VNN1CHRNB2CHRNA3 | |
| SCHEMBL19735106 | 0.74 | PIK3CD (0.37) | PIK3CDVNN1CHRNB2CHRNA3CHRNA4 | |
| SCHEMBL26295562 | 0.74 | OPRL1 (0.36) | HRH3KCNH2 | |
| SCHEMBL10119951 | 0.73 | CHRNB2 (0.57) | PIK3CDDPP4CHRNB2CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022074459-A2 | AUTOTAXIN INHIBITOR COMPOUNDS | ILDONG PHARMACEUTICAL CO., LTD. (KR) | 2022-04-14 | — | — | WO | disclosed |