Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 7/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30473867 | 0.83 | ACACB (0.51) | KDM4EGPR119KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL20474651 | 0.83 | ACACB (0.51) | KDM4EGPR119KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL17656733 | 0.77 | PDE10A (0.46) | ACACBHRH3 | |
| SCHEMBL20364268 | 0.77 | HSD17B10 (0.51) | KDM4E | |
| SCHEMBL24307477 | 0.74 | HRH3 (0.53) | GPR119KMT2AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL596004 | 0.73 | KDM4E (0.51) | KDM4EGPR119KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL4881099 | 0.73 | KDM4E (0.51) | KDM4EGPR119KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL16695108 | 0.73 | SMN1; SMN2 (0.56) | KDM4EGPR119KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL24844799 | 0.72 | CYP11B1 (0.47) | NPC1 | |
| SCHEMBL23246956 | 0.72 | SMN1; SMN2 (0.40) | KDM4EGPR119KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022074459-A2 | AUTOTAXIN INHIBITOR COMPOUNDS | ILDONG PHARMACEUTICAL CO., LTD. (KR) | 2022-04-14 | — | — | WO | disclosed |