Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | HPGDS | O60760 | 1/20 | 0.47 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.47 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12847405 | 0.92 | GPR119 (0.50) | GPR119KDM4EMAPTTHRBHPGD | |
| SCHEMBL31736580 | 0.88 | GPR119 (0.58) | GPR119KDM4EMAPTTHRBHPGD | |
| SCHEMBL12740695 | 0.88 | GPR119 (0.61) | GPR119KDM4EMAPTTHRBHPGD | |
| SCHEMBL23459591 | 0.86 | GPR119 (0.57) | GPR119KDM4EMAPTTHRBHPGD | |
| SCHEMBL31736852 | 0.86 | GPR119 (0.57) | GPR119KDM4EMAPTTHRBHPGD | |
| SCHEMBL23842631 | 0.86 | GPR119 (0.57) | GPR119KDM4EMAPTTHRBHPGD | |
| SCHEMBL25296230 | 0.86 | GPR119 (0.43) | GPR119KDM4EHPGDHPGDS | |
| SCHEMBL15001487 | 0.85 | GPR119 (0.62) | GPR119KDM4EMAPTTHRBHPGD | |
| SCHEMBL7478208 | 0.85 | GPR119 (0.65) | GPR119KDM4EMAPTTHRBHPGDS | |
| SCHEMBL23094480 | 0.84 | GPR119 (0.61) | GPR119KDM4EMAPTTHRBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240246961-A1 | AUTOTAXIN INHIBITOR COMPOUNDS | ILDONG PHARMACEUTICAL CO., LTD. (KR) | 2024-07-25 | — | — | US | disclosed |
| US-11970493-B2 | Autotaxin inhibitor compounds | ILDONG PHARMACEUTICAL CO., LTD. (KR) | 2024-04-30 | — | — | US | disclosed |
| EP-4323369-A1 | THIENOPYRROLE COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2024-02-21 | — | — | EP | disclosed |
| CN-117120450-A | Thienopyrrole compounds | 吉利德科学公司 | 2023-11-24 | — | — | CN | disclosed |
| US-20230365594-A1 | THIENOPYRROLE COMPOUNDS | GILEAD SCIENCES, INC. | 2023-11-16 | — | — | US | disclosed |
| EP-4225756-A2 | AUTOTAXIN INHIBITOR COMPOUNDS | Ildong Pharmaceutical Co., Ltd. (KR) | 2023-08-16 | — | — | EP | disclosed |
| CN-116322692-A | Autotaxin inhibitor compounds | 日东制药株式会社 | 2023-06-23 | — | — | CN | disclosed |
| US-11661431-B2 | Thienopyrrole compounds | GILEAD SCIENCES, INC. (US) | 2023-05-30 | — | — | US | disclosed |
| US-20220389034-A1 | THIENOPYRROLE COMPOUNDS | GILEAD SCIENCES, INC. | 2022-12-08 | — | — | US | disclosed |
| WO-2022221642-A1 | THIENOPYRROLE COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2022-10-20 | — | — | WO | disclosed |
| WO-2022074459-A2 | AUTOTAXIN INHIBITOR COMPOUNDS | ILDONG PHARMACEUTICAL CO., LTD. (KR) | 2022-04-14 | — | — | WO | disclosed |
| WO-2022074459-A2 | AUTOTAXIN INHIBITOR COMPOUNDS | ILDONG PHARMACEUTICAL CO., LTD. (KR) | 2022-04-14 | — | — | WO | disclosed |
| US-20220106311-A1 | AUTOTAXIN INHIBITOR COMPOUNDS | ILDONG PHARMACEUTICAL CO., LTD. (KR) | 2022-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230365594-A1 | THIENOPYRROLE COMPOUNDS | SSB, TPMT, LCP2 | GPR119 3470/4885KDM4E 1774/4885MAPT 3260/4885 |
| US-11661431-B2 | Thienopyrrole compounds | SSB, TPMT, LCP2 | GPR119 3470/4885KDM4E 1774/4885MAPT 3260/4885 |
| US-20240246961-A1 | AUTOTAXIN INHIBITOR COMPOUNDS | ENPP2, ATXN10, ATXN2L | GPR119 4007/4885KDM4E 1416/4885MAPT 739/4885 |
| US-20220106311-A1 | AUTOTAXIN INHIBITOR COMPOUNDS | ENPP2, ATXN10, ATXN2L | GPR119 4007/4885KDM4E 1416/4885MAPT 739/4885 |
| US-20220389034-A1 | THIENOPYRROLE COMPOUNDS | SSB, TPMT, LCP2 | GPR119 3470/4885KDM4E 1774/4885MAPT 3260/4885 |
| US-11970493-B2 | Autotaxin inhibitor compounds | ENPP2, ATXN10, ATXN2L | GPR119 4007/4885KDM4E 1416/4885MAPT 739/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.