Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 5/20 | 0.35 |
| ▸ | RAB9A | P51151 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.32 |
| ▸ | FBP1 | P09467 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15337285 | 0.81 | NPC1 (0.44) | ELANENPC1RAB9AMAPTMEN1 | |
| SCHEMBL17708107 | 0.79 | ELANE (0.34) | ELANENPC1RAB9AMAPTMEN1 | |
| SCHEMBL18062406 | 0.78 | ELANE (0.36) | ELANENPC1RAB9AMAPTMEN1 | |
| SCHEMBL21604555 | 0.77 | L3MBTL1 (0.41) | ELANENPC1RAB9AMAPTMEN1 | |
| SCHEMBL30316275 | 0.77 | L3MBTL1 (0.41) | ELANENPC1RAB9AMAPTMEN1 | |
| SCHEMBL30408785 | 0.76 | NPC1 (0.33) | ELANENPC1RAB9AMAPTMEN1 | |
| SCHEMBL24251878 | 0.76 | NPC1 (0.33) | ELANENPC1RAB9AMAPTMEN1 | |
| SCHEMBL24313003 | 0.74 | NPC1 (0.32) | ELANENPC1RAB9AMAPTMEN1 | |
| SCHEMBL30437347 | 0.74 | NPC1 (0.32) | ELANENPC1RAB9AMAPTMEN1 | |
| SCHEMBL24313065 | 0.74 | ESR1 (0.37) | MAPTESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116096720-B | Dihydropyrrolo [2,3-d ] pyridazin-7-one derivatives, preparation method and application thereof | 上海和誉生物医药科技有限公司 | 2025-02-07 | — | — | CN | disclosed |
| CN-115867547-B | 1H-pyrazole-4-amide derivative, preparation method and application thereof | 上海和誉生物医药科技有限公司 | 2024-12-20 | — | — | CN | disclosed |
| CN-116096720-A | Dihydropyrrolo [2,3-d ] pyridazin-7-one derivatives, preparation method and application thereof | 上海和誉生物医药科技有限公司 | 2023-05-09 | — | — | CN | disclosed |
| CN-115867547-A | 1H-pyrazole-4-amide derivative, and preparation method and application thereof | 上海和誉生物医药科技有限公司 | 2023-03-28 | — | — | CN | disclosed |
| WO-2022042612-A1 | DIHYDROPYRROLO[2,3-D]PYRIDAZIN-7-ONE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 上海和誉生物医药科技有限公司 | 2022-03-03 | — | — | WO | disclosed |