Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 20/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7875528 | 0.81 | HRH3 (0.43) | HRH3KCNH2CYP2D6 | |
| SCHEMBL104632 | 0.76 | HRH3 (0.63) | HRH3KCNH2CYP2D6 | |
| SCHEMBL14453913 | 0.74 | HRH3 (0.66) | HRH3KCNH2CYP2D6 | |
| SCHEMBL19004863 | 0.73 | ALDH1A1 (0.61) | HRH3KCNH2CYP2D6 | |
| SCHEMBL25911208 | 0.73 | HRH3 (0.45) | HRH3KCNH2CYP2D6 | |
| SCHEMBL23312164 | 0.73 | HRH3 (0.45) | HRH3KCNH2CYP2D6 | |
| SCHEMBL20315424 | 0.73 | ALDH1A1 (0.67) | HRH3KCNH2CYP2D6 | |
| SCHEMBL13047476 | 0.73 | HRH3 (0.47) | HRH3KCNH2CYP2D6 | |
| SCHEMBL26680011 | 0.72 | HRH3 (0.66) | HRH3KCNH2CYP2D6 | |
| SCHEMBL13503770 | 0.72 | ALDH1A1 (0.70) | HRH3KCNH2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3784666-B1 | ANTIPROLIFERATION COMPOUNDS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2022-03-16 | — | — | EP | disclosed |