Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.45 |
| ▸ | RYR2 | Q92736 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9636752 | 0.78 | RYR2 (0.61) | MEN1ALDH1A1GAAKMT2ANOX1 | |
| SCHEMBL10226479 | 0.77 | GAA (0.53) | MEN1ALDH1A1GAAKMT2ARYR2 | |
| SCHEMBL23520056 | 0.74 | KDM4E (0.44) | MEN1ALDH1A1GAAKMT2ANOX1 | |
| SCHEMBL1816443 | 0.73 | MEN1 (0.53) | MEN1ALDH1A1GAAKMT2ARYR2 | |
| SCHEMBL6204345 | 0.73 | MEN1 (0.53) | MEN1ALDH1A1GAAKMT2ARYR2 | |
| SCHEMBL8038619 | 0.73 | MEN1 (0.53) | MEN1ALDH1A1GAAKMT2ARYR2 | |
| SCHEMBL616341 | 0.73 | MEN1 (0.53) | MEN1ALDH1A1GAAKMT2ANOX1 | |
| SCHEMBL24654710 | 0.72 | ALDH1A1 (0.49) | MEN1ALDH1A1GAAKMT2ANOX1 | |
| SCHEMBL12692912 | 0.72 | ALDH1A1 (0.49) | MEN1ALDH1A1GAAKMT2ARYR2 | |
| SCHEMBL30804421 | 0.72 | RYR2 (0.63) | MEN1ALDH1A1GAAKMT2ANOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3784666-B1 | ANTIPROLIFERATION COMPOUNDS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2022-03-16 | — | — | EP | disclosed |