Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RYR2 | Q92736 | 2/20 | 0.61 |
| ▸ | CDK1 | P06493 | 2/20 | 0.37 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.37 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.37 |
| ▸ | CLK2 | P49760 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.37 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.37 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.37 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.37 |
| ▸ | BRSK1 | Q8TDC3 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2600209 | 0.80 | RYR2 (0.66) | RYR2PARP10ALDH1A1GAAPARP11 | |
| SCHEMBL9635092 | 0.78 | RYR2 (0.52) | RYR2CDK1PARP10PRKD1ALDH1A1 | |
| SCHEMBL24313441 | 0.78 | MEN1 (0.49) | RYR2NOX1ALDH1A1GAAMEN1 | |
| SCHEMBL1238947 | 0.76 | RYR2 (0.61) | RYR2CDK1PARP10PRKD1ALDH1A1 | |
| SCHEMBL629534 | 0.76 | RYR2 (1.00) | RYR2CDK1CDK2PRKD1ALDH1A1 | |
| SCHEMBL17892772 | 0.74 | RYR2 (0.84) | RYR2CDK1CDK2PRKD1ALDH1A1 | |
| SCHEMBL20883874 | 0.73 | PARP10 (0.63) | CDK1DAPK3DYRK3MAP4K4PIM1 | |
| SCHEMBL24460532 | 0.73 | PARP1 (0.57) | RYR2PIM1NOX1PARP10PARP11 | |
| SCHEMBL5850195 | 0.72 | RYR2 (0.55) | RYR2GSK3BPARP10ALDH1A1GAA | |
| SCHEMBL9636480 | 0.72 | RYR2 (0.56) | RYR2ALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0368063-B1 | PROCESS FOR THE CHLORINATION IN THE NUCLEUS OF AROMATIC HYDROCARBONS | BAYER AG (DE) | 1992-06-10 | — | — | EP | disclosed |
| US-4990707-A | Process for the ring chlorination of aromatic hydrocarbons | BAYER AKTIENGESELLSCHAFT (DE) | 1991-02-05 | — | — | US | disclosed |
| EP-0368063-A1 | Process for the chlorination in the nucleus of aromatic hydrocarbons | BAYER AG (DE) | 1990-05-16 | — | — | EP | disclosed |