SCHEMBL24313477

SCHEMBL24313477

Clc1cc(NC2COC2)ccc1C1COCCCN1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KAT2B Q92831 1/20 0.32
KCNH2 Q12809 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21491118 0.78 SLC6A2 (0.38) KCNH2
SCHEMBL31472352 0.78 SLC6A2 (0.38) KCNH2
SCHEMBL21491275 0.78 ESR1 (0.38)
SCHEMBL31472302 0.78 CDC7 (0.33)
SCHEMBL21491362 0.78 CDC7 (0.33)
SCHEMBL31472367 0.78 ESR1 (0.38)
SCHEMBL21491281 0.75 CYP11B2 (0.39)
SCHEMBL31472438 0.75 CYP11B2 (0.39)
SCHEMBL29456404 0.75 CYP11B2 (0.39)
SCHEMBL24313232 0.75 SLC6A2 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4043460-A1 ANTIPROLIFERATION COMPOUNDS AND USES THEREOF Merck Patent GmbH (DE) 2022-08-17 EP disclosed
EP-3784666-B1 ANTIPROLIFERATION COMPOUNDS AND USES THEREOF MERCK PATENT GMBH (DE) 2022-03-16 EP disclosed