Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 12/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21491275 | 1.00 | ESR1 (0.38) | ESR1DRD2DRD3ESR2HSD17B10 | |
| SCHEMBL21491310 | 0.89 | DRD2 (0.37) | DRD2DRD3HSD17B10 | |
| SCHEMBL29456570 | 0.89 | DRD2 (0.37) | DRD2DRD3HSD17B10 | |
| SCHEMBL21491362 | 0.83 | CDC7 (0.33) | — | |
| SCHEMBL31472302 | 0.83 | CDC7 (0.33) | — | |
| SCHEMBL21491281 | 0.81 | CYP11B2 (0.39) | DRD2DRD3 | |
| SCHEMBL31472352 | 0.81 | SLC6A2 (0.38) | — | |
| SCHEMBL31472438 | 0.81 | CYP11B2 (0.39) | DRD2DRD3 | |
| SCHEMBL21491118 | 0.81 | SLC6A2 (0.38) | — | |
| SCHEMBL29456404 | 0.81 | CYP11B2 (0.39) | DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112236428-B | Antiproliferative compounds and uses thereof | 默克专利股份有限公司 | 2025-04-01 | — | — | CN | disclosed |