SCHEMBL24313495

SCHEMBL24313495

CN1C(C)(C)CC(OC(=O)CCC(CCC(=O)OC2CC(C)(C)N(C)C(C)(C)C2)(C(=O)OC2CC(C)(C)N(C)C(C)(C)C2)C(=O)OC2CC(C)(C)N(C)C(C)(C)C2)CC1(C)C

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.33
GAA P10253 1/20 0.33
KMT2A Q03164 1/20 0.33
TP53 P04637 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11455499 0.84 KMT2A (0.37) MEN1GAAKMT2AALDH1A1TSHR
Suxemerid SCHEMBL2779070 0.84 SMN1; SMN2 (0.39) MEN1GAAKMT2ATP53SMN1; SMN2
SCHEMBL27050094 0.83 CHRM3 (0.34) TP53SMN1; SMN2ALDH1A1
SCHEMBL314125 0.82 MEN1 (0.31) MEN1GAAKMT2A
SCHEMBL11169049 0.81 MLNR (0.32) MEN1GAAKMT2AALDH1A1TSHR
SCHEMBL5649676 0.81 SMN1; SMN2 (0.44) MEN1GAAKMT2ATP53SMN1; SMN2
SCHEMBL463020 0.81 SMN1; SMN2 (0.47) MEN1GAAKMT2ATP53SMN1; SMN2
SCHEMBL30744 0.80 NAAA (0.47) MEN1GAAKMT2ATP53SMN1; SMN2
SCHEMBL12244967 0.80 NAAA (0.47) MEN1GAAKMT2ATP53SMN1; SMN2
SCHEMBL21127012 0.80 NAAA (0.47) MEN1GAAKMT2ATP53SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3947540-B1 METHOD FOR STABILIZING THERMOPLASTIC RECYCLATES, STABILIZED PLASTIC COMPOSITIONS, AND MOLDING COMPOUNDS AND MOLDED PARTS PRODUCED THEREFROM FRAUNHOFER GES FORSCHUNG (DE) 2023-08-16 EP disclosed
US-20230117792-A1 USE OF SUBSTITUTED CINNAMIC ACID ESTERS AS STABILISERS FOR ORGANIC MATERIALS, STABILISED ORGANIC MATERIAL, METHOD FOR STABILISING ORGANIC MATERIALS AND SPECIFIC CINNAMIC ACID ESTERS Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2023-04-20 US disclosed
US-20230119120-A1 USE OF HYDROXYCINNAMIC ACID SALTS FOR STABILIZING ORGANIC MATERIALS, STABILIZED ORGANIC MATERIAL, METHOD FOR STABILIZING ORGANIC MATERIALS, SPECIFIC STABILIZERS AND STABILIZER COMPOSITIONS Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2023-04-20 US disclosed
WO-2022194672-A1 USE OF A STABILIZER COMPOSITION FOR STABILIZING POLYOLEFIN RECYCLATES, STABILIZER COMPOSITION, MASTER BATCH CONCENTRATE, PLASTIC COMPOSITION, MOLDING COMPOUND OR MOLDING, METHOD FOR STABILIZING A POLYOLEFIN RECYCLATE AND USE OF A PLASTIC COMPOSITION Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2022-09-22 WO disclosed
US-20220162422-A1 METHOD FOR STABILIZING THERMOPLASTIC RECYCLATES, STABILIZED PLASTIC COMPOSITIONS, AND MOLDING COMPOUNDS AND MOLDED PARTS PRODUCED THEREFROM Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e. V. (DE) 2022-05-26 US disclosed
US-20220119624-A1 METHOD OF STABILIZING HALOGEN-FREE THERMOPLASTIC RECYCLATES, PLASTICS COMPOSITION, STABILIZER COMPOSITION AND USE OF THE STABILIZER COMPOSITION Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e. V. (DE) 2022-04-21 US disclosed
WO-2022058371-A1 USE OF DIEUGENOL, OLIGOMERS AND/OR POLYMERS OF EUGENOL FOR STABILIZING ORGANIC MATERIALS, STABILIZED PLASTICS COMPOSITION, STABILIZER COMPOSITION AND METHOD FOR STABILIZING ORGANIC MATERIALS Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2022-03-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230117792-A1 USE OF SUBSTITUTED CINNAMIC ACID ESTERS AS STABILISERS FOR ORGANIC MATERIALS, STABILISED ORGANIC MATERIAL, METHOD FOR STABILISING ORGANIC MATERIALS AND SPECIFIC CINNAMIC ACID ESTERS TECR, NISCH, CAD MEN1 2112/4885GAA 44/4885KMT2A 3233/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.