Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 5/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24313966 | 0.93 | UGCG (0.35) | ALDH1A1LMNAKCNH2GAAMRGPRX1 | |
| SCHEMBL24314235 | 0.92 | KCNH2 (0.36) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL24313660 | 0.92 | KCNH2 (0.35) | MEN1KMT2AMAPTALDH1A1L3MBTL1 | |
| SCHEMBL24313761 | 0.89 | MEN1 (0.32) | MEN1KMT2AMAPTALDH1A1L3MBTL1 | |
| SCHEMBL24313750 | 0.89 | KAT2B (0.33) | ALDH1A1KCNH2KDM4EHTTHPGD | |
| SCHEMBL24313661 | 0.89 | KCNK3 (0.36) | MEN1KMT2AMAPTALDH1A1L3MBTL1 | |
| SCHEMBL24314229 | 0.89 | PTGS2 (0.35) | MEN1KMT2AMAPTALDH1A1L3MBTL1 | |
| SCHEMBL24314298 | 0.89 | MEN1 (0.33) | MEN1KMT2AMAPTALDH1A1L3MBTL1 | |
| SCHEMBL24314200 | 0.88 | MEN1 (0.35) | MEN1KMT2AMAPTALDH1A1L3MBTL1 | |
| SCHEMBL24314220 | 0.88 | KDM4E (0.33) | MEN1KMT2AMAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081842-A1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | THE BROAD INSTITUTE, INC. (US) | 2022-04-21 | — | — | WO | disclosed |