Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CCR5 | P51681 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | TRPC6 | Q9Y210 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24313754 | 0.89 | MEN1 (0.36) | MEN1KMT2ACCR5MAPTNPSR1 | |
| SCHEMBL24314310 | 0.88 | SSTR5 (0.34) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL24314235 | 0.88 | KCNH2 (0.36) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL24313761 | 0.85 | MEN1 (0.32) | MEN1KMT2AMAPTNPSR1ALDH1A1 | |
| SCHEMBL24313977 | 0.85 | CYP1A2 (0.37) | MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL24313682 | 0.85 | ALDH1A1 (0.34) | MEN1KMT2ACCR5MAPTNPSR1 | |
| SCHEMBL24314303 | 0.84 | MEN1 (0.35) | MEN1KMT2AMAPTNPSR1ALDH1A1 | |
| SCHEMBL24313660 | 0.83 | KCNH2 (0.35) | MEN1KMT2AMAPTNPSR1ALDH1A1 | |
| SCHEMBL24313966 | 0.82 | UGCG (0.35) | ALDH1A1LMNASMN1; SMN2GAA | |
| SCHEMBL24314298 | 0.81 | MEN1 (0.33) | MEN1KMT2AMAPTNPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081842-A1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | THE BROAD INSTITUTE, INC. (US) | 2022-04-21 | — | — | WO | disclosed |