SCHEMBL2431398

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2430687	1.00	ITGB1 (0.37)	ITGB1ITGA4ALDH1A1NPC1RAB9A
	SCHEMBL2433075	0.89	KIT (0.36)	ACKR3DGAT1KDM4E
	SCHEMBL12329093	0.89	KIT (0.36)	ACKR3DGAT1KDM4E
	SCHEMBL2433078	0.89	KIT (0.36)	ACKR3DGAT1KDM4E
	SCHEMBL2430579	0.88	GRM4 (0.44)	ALDH1A1NPC1RAB9ADGAT1TP53
	SCHEMBL2430852	0.88	GRM4 (0.44)	ALDH1A1NPC1RAB9ADGAT1TP53
	SCHEMBL2431767	0.87	DGAT1 (0.38)	DGAT1GRM4
	SCHEMBL2435714	0.87	DGAT1 (0.38)	DGAT1GRM4
	SCHEMBL2431730	0.87	ACKR3 (0.36)	ACKR3DGAT1
	SCHEMBL2431723	0.87	ACKR3 (0.36)	ACKR3DGAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.