Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 4/20 | 0.50 |
| ▸ | AVPR1A | P37288 | 6/20 | 0.49 |
| ▸ | OXTR | P30559 | 4/20 | 0.49 |
| ▸ | AVPR2 | P30518 | 3/20 | 0.49 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.48 |
| ▸ | VHL | P40337 | 1/20 | 0.45 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.45 |
| ▸ | GHSR | Q92847 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19270360 | 1.00 | FFAR2 (0.50) | FFAR2AVPR1AOXTRAVPR2PIK3CD | |
| SCHEMBL5477136 | 1.00 | FFAR2 (0.50) | FFAR2AVPR1AOXTRAVPR2PIK3CD | |
| SCHEMBL29449381 | 1.00 | FFAR2 (0.50) | FFAR2AVPR1AOXTRAVPR2PIK3CD | |
| SCHEMBL31156208 | 0.87 | AVPR1A (0.49) | FFAR2AVPR1AOXTRAVPR2PIK3CD | |
| SCHEMBL28754781 | 0.87 | PIK3CD (0.44) | AVPR1AOXTRAVPR2PIK3CDVHL | |
| SCHEMBL4424510 | 0.86 | PIK3CD (0.52) | FFAR2PIK3CDVHLSLC6A7ATM | |
| SCHEMBL9028119 | 0.83 | PIK3CD (0.61) | PIK3CDVHLATM | |
| SCHEMBL10469223 | 0.83 | PIK3CD (0.61) | PIK3CDVHLATM | |
| SCHEMBL9028110 | 0.83 | PIK3CD (0.61) | PIK3CDVHLATM | |
| SCHEMBL2459843 | 0.83 | PIK3CD (0.61) | PIK3CDVHLATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3252037-B1 | PROCESS FOR THE PREPARATION OF (3Z,5S)-5-(HYDROXYMETHYL)-1-[(2´-METHYL-1,1´-BIPHENYL-4-YL)CARBONYL)PYRROLIDIN-3-ONE O-METHYLOXIME | ObsEva SA (CH) | 2022-03-09 | — | — | EP | disclosed |