Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 10/20 | 0.37 |
| ▸ | STK17B | O94768 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953328 | 0.85 | HTR3A (0.43) | HTR3ASTK17BCHRNA7MAPK14CYP3A4 | |
| SCHEMBL7897734 | 0.85 | HTR3A (0.43) | HTR3ASTK17BCHRNA7MAPK14CYP3A4 | |
| SCHEMBL18727360 | 0.83 | HTR3A (0.39) | HTR3ASTK17BCHRNA7MAPK14CYP3A4 | |
| SCHEMBL7893855 | 0.73 | IRAK4 (0.51) | HTR3ACHRNA7CYP3A4HIF1ALMNA | |
| SCHEMBL12928902 | 0.72 | HTR3A (0.41) | HTR3ACHRNA7CYP3A4HIF1ALMNA | |
| SCHEMBL18727274 | 0.71 | HTR3A (0.36) | HTR3ASTK17BCHRNA7MAPK14CYP3A4 | |
| SCHEMBL12066727 | 0.69 | CYP1A2 (0.43) | HTR3ACHRNA7CYP3A4HIF1ALMNA | |
| SCHEMBL29955343 | 0.65 | ENPP2 (0.39) | HTR3ASTK17BSMN1; SMN2ABCC9EPHX2 | |
| SCHEMBL7893688 | 0.65 | ENPP2 (0.39) | HTR3ASTK17BSMN1; SMN2ABCC9EPHX2 | |
| SCHEMBL7891357 | 0.65 | EGFR (0.39) | HTR3ACHRNA7MAPK14CYP3A4HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3153023-B1 | BENZOXAZOLE KINASE INHIBITORS AND METHODS OF USE | TAKEDA PHARMACEUTICALS CO (JP) | 2022-03-16 | — | — | EP | disclosed |