Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX1 | Q96LB2 | 7/20 | 0.38 |
| ▸ | TSPO | P30536 | 2/20 | 0.38 |
| ▸ | ALPL | P05186 | 5/20 | 0.37 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24314247 | 0.94 | MEN1 (0.36) | MRGPRX1TSPOKAT6AMEN1KMT2A | |
| SCHEMBL24313659 | 0.93 | MRGPRX1 (0.36) | MRGPRX1TSPOKAT6AMCHR1KCNH2 | |
| SCHEMBL24313753 | 0.92 | MEN1 (0.38) | MRGPRX1TSPOKAT6AMEN1KMT2A | |
| SCHEMBL24313760 | 0.90 | SCN9A (0.35) | MEN1KMT2AL3MBTL1TSHR | |
| SCHEMBL24313686 | 0.90 | ALDH1A1 (0.44) | ALPLMCHR1KCNH2MEN1KMT2A | |
| SCHEMBL24314300 | 0.90 | ALDH1A1 (0.38) | MRGPRX1TSPOALPLMCHR1KCNH2 | |
| SCHEMBL24313979 | 0.90 | CYP1A2 (0.37) | ALPLMCHR1KCNH2MEN1KMT2A | |
| SCHEMBL24314309 | 0.88 | SCN7A (0.37) | ALPLMCHR1MEN1KMT2AL3MBTL1 | |
| SCHEMBL24314230 | 0.88 | MEN1 (0.36) | KAT6AMEN1KMT2A | |
| SCHEMBL24313965 | 0.85 | LMNA (0.38) | MRGPRX1KAT6AMCHR1KCNH2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4229045-B1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | BROAD INST INC (US) | 2025-11-12 | — | — | EP | claimed |
| EP-4229045-A1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | The Broad Institute Inc. (US) | 2023-08-23 | — | — | EP | claimed |
| WO-2022081842-A1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | THE BROAD INSTITUTE, INC. (US) | 2022-04-21 | — | — | WO | claimed |
| EP-4229045-A1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | The Broad Institute Inc. (US) | 2023-08-23 | — | — | EP | disclosed |
| WO-2022081842-A1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | THE BROAD INSTITUTE, INC. (US) | 2022-04-21 | — | — | WO | disclosed |
| WO-2022081842-A1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | THE BROAD INSTITUTE, INC. (US) | 2022-04-21 | — | — | WO | disclosed |