SCHEMBL24314846

SCHEMBL24314846

Clc1ccc2oc3cccc(-c4nc(C5=CCCC=C5)nc(-c5ccccc5)n4)c3c2c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 3/20 0.36
ADORA3 P0DMS8 2/20 0.36
TNKS O95271 1/20 0.36
MAPK1 P28482 2/20 0.35
NPC1 O15118 1/20 0.35
HTT P42858 1/20 0.35
RAB9A P51151 1/20 0.35
CASP3 P42574 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
SENP7 Q9BQF6 1/20 0.34
SENP6 Q9GZR1 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
KMT2A Q03164 3/20 0.33
KDM4E B2RXH2 1/20 0.33
PDE5A O76074 2/20 0.33
ABCG2 Q9UNQ0 1/20 0.33
GABRP O00591 1/20 0.33
GABRD O14764 1/20 0.33
GABRA1 P14867 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20982420 0.95 AHR (0.36) AHRADORA3TNKSMAPK1NPC1
SCHEMBL24427482 0.93 PIM1 (0.35) AHRTNKSNPC1RAB9ACASP3
SCHEMBL26899558 0.90 PLA2G2A (0.34) GAAPIM1CSNK2A2CSNK2BPIM3
SCHEMBL19802902 0.89 PLA2G2A (0.34) GAAPIM1CSNK2A2CSNK2BPIM3
SCHEMBL23783987 0.88 KDM4E (0.36) MAPK1NPC1HTTRAB9ACASP3
SCHEMBL19802695 0.88 PLA2G2A (0.34) GAAPIM1CSNK2A2CSNK2BPIM3
SCHEMBL19802125 0.87 AHR (0.47) AHRADORA3TNKSMAPK1NPC1
SCHEMBL30737668 0.87 AHR (0.47) AHRADORA3TNKSMAPK1NPC1
SCHEMBL22916353 0.87 BACE1 (0.30) AHR
SCHEMBL24657753 0.86 BACE1 (0.33) ADORA3MAPK1SMN1; SMN2KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3972001-A1 ORGANIC LIGHT EMITTING DEVICE LG Chem, Ltd. (KR) 2022-03-23 EP disclosed