SCHEMBL2431498

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1136082	0.82	ALDH1A1 (0.40)	ALDH1A1ESR1ESR2RETEGFR
	SCHEMBL2435652	0.79	MGAM (0.40)	RETNPC1RAB9APOLBMGAM
	SCHEMBL1136218	0.71	EGFR (0.44)	ALDH1A1RETEGFRMEN1NPC1
	SCHEMBL11051124	0.68	ALDH1A1 (0.68)	ALDH1A1ESR1ESR2EGFRSRC
	SCHEMBL2433369	0.67	IDO1 (0.36)	ALDH1A1EGFRMEN1NPC1TP53
	SCHEMBL7261266	0.67	ALDH1A1 (0.46)	ALDH1A1RETEGFRMEN1NPC1
	SCHEMBL26996335	0.66	KDM4E (0.42)	ALDH1A1ESR1ESR2TP53MAPT
	SCHEMBL31506193	0.66	KDM4E (0.42)	ALDH1A1ESR1ESR2TP53MAPT
	SCHEMBL10648146	0.64	CCNE2 (0.43)	ESR1ESR2RETMAOBCCNE2
	SCHEMBL21563888	0.63	PARP1 (0.52)	ALDH1A1EGFRSRCMEN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.