SCHEMBL24315218

SCHEMBL24315218

CC1C=Cc2cccc(-c3cccc(N(c4ccc(-c5ccc(-c6ccccc6)cc5)cc4)c4ccc(-c5cc6ccccc6c6ccccc56)cc4)c3)c2C1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
MPI P34949 1/20 0.31
KMT2A Q03164 1/20 0.31
CRHR1 P34998 1/20 0.31
HTR1A P08908 5/20 0.31
HTR7 P34969 5/20 0.31
CHRNA1 P02708 1/20 0.30
CHRNG P07510 1/20 0.30
CHRNB1 P11230 1/20 0.30
CHRNB2 P17787 1/20 0.30
SLC6A2 P23975 1/20 0.30
CHRNB4 P30926 1/20 0.30
SLC6A4 P31645 1/20 0.30
CHRNA3 P32297 1/20 0.30
CHRNA4 P43681 1/20 0.30
SLC6A3 Q01959 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24154513 0.86 HTR1A (0.34) HTR1AHTR7
SCHEMBL24315302 0.84 CYP11B1 (0.30)
SCHEMBL25654185 0.82 HTR7 (0.31) ALDH1A1HPGDHTR1AHTR7
SCHEMBL25654195 0.80 HTR7 (0.33) HTR1AHTR7CHRNA1CHRNGCHRNB1
SCHEMBL23447765 0.80 MCL1 (0.44) KDM4EMEN1ALDH1A1MAPTHPGD
SCHEMBL23224968 0.80 MCL1 (0.44) KDM4EMEN1ALDH1A1MAPTHPGD
SCHEMBL23225029 0.80 MCL1 (0.44) KDM4EMEN1ALDH1A1MAPTHPGD
SCHEMBL24839245 0.80 MCL1 (0.44) KDM4EMEN1ALDH1A1MAPTHPGD
SCHEMBL29773009 0.80 CYP11B1 (0.41) KDM4EMEN1ALDH1A1MAPTHPGD
SCHEMBL23471889 0.80 CYP11B1 (0.43) KDM4EMEN1ALDH1A1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3972001-B1 ORGANIC LIGHT EMITTING DEVICE LG CHEMICAL LTD (KR) 2023-06-21 EP disclosed
EP-3972001-A1 ORGANIC LIGHT EMITTING DEVICE LG Chem, Ltd. (KR) 2022-03-23 EP disclosed