Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.60 |
| ▸ | HTR2C | P28335 | 4/20 | 0.60 |
| ▸ | HTR2B | P41595 | 3/20 | 0.60 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1869057 | 0.91 | HTR2A (0.55) | HTR2AHTR2CHTR2BNOTUMBRD4 | |
| SCHEMBL13276577 | 0.91 | HTR2A (0.55) | HTR2AHTR2CHTR2BNOTUMBRD4 | |
| SCHEMBL17339956 | 0.90 | HTR2A (0.54) | HTR2AHTR2CHTR2BNOTUMBRD4 | |
| Fluorobenzene SCHEMBL27513534 | 0.78 | ALDH1A1 (0.47) | HTR2AHTR2CHTR2BALDH1A1CHRM2 | |
| SCHEMBL6942296 | 0.75 | SRD5A1 (0.48) | HTR2AHTR2CHTR2BNOTUMCHRM2 | |
| SCHEMBL7733992 | 0.74 | NOTUM (0.55) | HTR2AHTR2CHTR2BNOTUMLMNA | |
| SCHEMBL6890897 | 0.74 | NOTUM (0.55) | HTR2AHTR2CHTR2BNOTUMLMNA | |
| SCHEMBL31672940 | 0.74 | NOTUM (0.55) | HTR2AHTR2CHTR2BNOTUMLMNA | |
| SCHEMBL14705297 | 0.74 | NOTUM (0.55) | HTR2AHTR2CHTR2BNOTUMLMNA | |
| SCHEMBL811795 | 0.74 | NOTUM (0.55) | HTR2AHTR2CHTR2BNOTUMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3974423-A1 | INDOLE DERIVATIVE-CONTAINING INHIBITOR, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Shanghai Hansoh Biomedical Co., Ltd. (CN) | 2022-03-30 | — | — | EP | disclosed |