Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | NSD2 | O96028 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.47 |
| ▸ | LIPE | Q05469 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2760548 | 0.82 | RIPK1 (0.60) | RIPK1TDP1NSD2ALDH1A1LMNA | |
| SCHEMBL12039097 | 0.81 | RIPK1 (0.58) | RIPK1TDP1NSD2ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL3225116 | 0.80 | RIPK1 (0.54) | RIPK1TDP1NSD2ALDH1A1LMNA | |
| SCHEMBL25384725 | 0.80 | ALDH1A1 (0.47) | RIPK1TDP1NSD2ALDH1A1MCHR1 | |
| SCHEMBL967112 | 0.80 | NPC1 (0.66) | RIPK1ALDH1A1KMT2AAOC3RAB9A | |
| Hydrochloric Acid SCHEMBL27945133 | 0.78 | NPC1 (0.63) | RIPK1ALDH1A1KMT2AAOC3RAB9A | |
| SCHEMBL13223527 | 0.78 | RIPK1 (0.73) | RIPK1TDP1NSD2ALDH1A1LMNA | |
| SCHEMBL19027669 | 0.78 | RIPK1 (0.55) | RIPK1TDP1NSD2ALDH1A1LMNA | |
| SCHEMBL1959783 | 0.77 | RIPK1 (0.42) | RIPK1TDP1KMT2A | |
| SCHEMBL16257002 | 0.77 | BCL2A1 (0.56) | RIPK1TDP1NSD2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3974423-A1 | INDOLE DERIVATIVE-CONTAINING INHIBITOR, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Shanghai Hansoh Biomedical Co., Ltd. (CN) | 2022-03-30 | — | — | EP | disclosed |