SCHEMBL2431589

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2431591	1.00	KMT2A (0.37)	KMT2AMEN1ALDH1A1L3MBTL1CASP3
	SCHEMBL2434266	0.89	KMT2A (0.36)	KMT2AMEN1ALDH1A1L3MBTL1CASP3
	SCHEMBL2434263	0.89	KMT2A (0.36)	KMT2AMEN1ALDH1A1L3MBTL1CASP3
	SCHEMBL2431713	0.86	ALDH1A1 (0.44)	KMT2AMEN1ALDH1A1L3MBTL1CASP3
	SCHEMBL2431710	0.86	ALDH1A1 (0.44)	KMT2AMEN1ALDH1A1L3MBTL1CASP3
	SCHEMBL12329276	0.83	KDM4E (0.32)	ALDH1A1HTT
	SCHEMBL4153891	0.82	KDM4E (0.31)	HTT
	SCHEMBL4153886	0.82	KDM4E (0.31)	HTT
	SCHEMBL2432512	0.81	KDM4E (0.31)	HTT
	SCHEMBL2432517	0.81	KDM4E (0.31)	HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.