Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | SSTR3 | P32745 | 6/20 | 0.48 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.46 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.45 |
| ▸ | HRH2 | P25021 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26620816 | 0.86 | KDM1A (0.55) | KDM1AMAOBMAOASSTR3CARM1 | |
| SCHEMBL27010643 | 0.82 | KDM1A (0.47) | KDM1AMAOASSTR3L3MBTL1KDM4E | |
| SCHEMBL20063373 | 0.82 | KDM1A (0.47) | KDM1AMAOASSTR3L3MBTL1KDM4E | |
| SCHEMBL10882199 | 0.77 | KCNH2 (0.61) | KDM1AMAOBMAOACARM1PRMT6 | |
| SCHEMBL1041164 | 0.76 | KCNH2 (0.60) | KDM1AMAOBMAOACARM1PRMT6 | |
| SCHEMBL27010662 | 0.75 | ALDH1A1 (0.61) | KDM1AMAOBMAOAALDH1A1KDM4E | |
| SCHEMBL2732150 | 0.74 | CARM1 (0.63) | KDM1AMAOBMAOACARM1PRMT6 | |
| SCHEMBL27010659 | 0.74 | KDM1A (0.47) | KDM1AMAOBMAOASSTR3L3MBTL1 | |
| Hydrochloric Acid SCHEMBL4879048 | 0.72 | CARM1 (0.62) | KDM1AMAOBMAOACARM1PRMT6 | |
| SCHEMBL30779531 | 0.72 | TAAR1 (0.50) | MAOBMAOAATML3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081925-A1 | TRICYCLIC LIGANDS FOR DEGRADATION OF IKZF2 OR IKZF4 | C4 THERAPEUTICS, INC. (US) | 2022-04-21 | — | — | WO | disclosed |
| US-9585884-B2 | Pyrimidinone inhibitors of lipoprotein-associated phospholipase A2 | AUSPEX PHARMACEUTICALS, INC. (US) | 2017-03-07 | — | — | US | disclosed |