Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22647693 | 0.85 | PIM1 (0.41) | ALDH1A1HSD17B10KDM4EATMPIM1 | |
| SCHEMBL20061131 | 0.83 | ALDH1A1 (0.69) | ALDH1A1HSD17B10KDM4EEPHX1MGAM | |
| SCHEMBL4739291 | 0.83 | ALDH1A1 (0.69) | ALDH1A1HSD17B10KDM4EEPHX1MGAM | |
| SCHEMBL4417021 | 0.83 | PIM1 (0.42) | KDM4EATMPIM1L3MBTL1GAA | |
| SCHEMBL13303583 | 0.83 | PIM1 (0.42) | KDM4EATMPIM1L3MBTL1GAA | |
| SCHEMBL20061124 | 0.83 | PIM1 (0.42) | KDM4EATMPIM1L3MBTL1GAA | |
| SCHEMBL20061142 | 0.83 | ALDH1A1 (0.69) | ALDH1A1HSD17B10KDM4EEPHX1MGAM | |
| SCHEMBL20061122 | 0.80 | ALDH1A1 (0.62) | ALDH1A1HSD17B10KDM4EEPHX1MGAM | |
| SCHEMBL20061125 | 0.80 | ALDH1A1 (0.62) | ALDH1A1HSD17B10KDM4EEPHX1MGAM | |
| Hydrochloric Acid SCHEMBL6656735 | 0.78 | PIM1 (0.40) | KDM4EPIM1L3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081925-A1 | TRICYCLIC LIGANDS FOR DEGRADATION OF IKZF2 OR IKZF4 | C4 THERAPEUTICS, INC. (US) | 2022-04-21 | — | — | WO | disclosed |
| US-9585884-B2 | Pyrimidinone inhibitors of lipoprotein-associated phospholipase A2 | AUSPEX PHARMACEUTICALS, INC. (US) | 2017-03-07 | — | — | US | disclosed |