Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | BTK | Q06187 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14652326 | 0.81 | RXFP1 (0.34) | RXFP1ALDH1A1TDP1LMNAHPGD | |
| SCHEMBL11170777 | 0.74 | ALDH1A1 (0.61) | RXFP1ALDH1A1TDP1LMNAHTT | |
| SCHEMBL2723974 | 0.74 | ALDH1A1 (0.38) | RXFP1ALDH1A1TDP1LMNAHPGD | |
| SCHEMBL2724245 | 0.74 | ALDH1A1 (0.38) | RXFP1ALDH1A1TDP1LMNAHPGD | |
| SCHEMBL21112014 | 0.73 | RXFP1 (0.40) | RXFP1ALDH1A1TDP1LMNAHPGD | |
| SCHEMBL20379578 | 0.73 | RXFP1 (0.44) | RXFP1ALDH1A1TDP1LMNAHPGD | |
| SCHEMBL17171615 | 0.72 | RXFP1 (0.34) | RXFP1ALDH1A1TDP1LMNAHPGD | |
| SCHEMBL1025172 | 0.72 | ALDH1A1 (0.66) | ALDH1A1TDP1LMNAHPGDHTT | |
| SCHEMBL13103938 | 0.72 | ALDH1A1 (0.47) | ALDH1A1TDP1LMNAHPGDHTT | |
| SCHEMBL11508100 | 0.69 | NPC1 (0.53) | RXFP1ALDH1A1TDP1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022069383-A1 | MEMBRANES | FUJIFILM MANUFACTURING EUROPE BV (NL) | 2022-04-07 | — | — | WO | disclosed |
| US-9585884-B2 | Pyrimidinone inhibitors of lipoprotein-associated phospholipase A2 | AUSPEX PHARMACEUTICALS, INC. (US) | 2017-03-07 | — | — | US | disclosed |