Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2724245 | 0.80 | ALDH1A1 (0.38) | ALDH1A1TDP1L3MBTL1RXFP1LMNA | |
| SCHEMBL2723363 | 0.77 | TGM2 (0.42) | ALDH1A1LMNAKMT2A | |
| SCHEMBL24316347 | 0.74 | RXFP1 (0.40) | ALDH1A1TDP1L3MBTL1RXFP1LMNA | |
| SCHEMBL1025172 | 0.73 | ALDH1A1 (0.66) | ALDH1A1TDP1L3MBTL1LMNAKMT2A | |
| SCHEMBL27780197 | 0.72 | ALDH1A1 (0.48) | ALDH1A1TDP1L3MBTL1RXFP1LMNA | |
| SCHEMBL9133237 | 0.71 | TDP1 (0.39) | ALDH1A1TDP1L3MBTL1RXFP1LMNA | |
| SCHEMBL9133003 | 0.71 | TDP1 (0.39) | ALDH1A1TDP1L3MBTL1RXFP1LMNA | |
| SCHEMBL9096561 | 0.71 | GPR35 (0.39) | ALDH1A1TDP1L3MBTL1RXFP1KMT2A | |
| SCHEMBL11170777 | 0.71 | ALDH1A1 (0.61) | ALDH1A1TDP1L3MBTL1RXFP1LMNA | |
| SCHEMBL8766073 | 0.70 | ALDH1A1 (0.44) | ALDH1A1TDP1L3MBTL1RXFP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4612392-A | N-substituted acrylamide and methacrylamide derivatives and their preparation | BASF AKTIENGESELLSCHAFT (DE) | 1986-09-16 | — | — | US | claimed |
| US-10023782-B2 | Salt-tolerant, thermally-stable rheology modifiers | ISP INVESTMENTS LLC (US) | 2018-07-17 | — | — | US | disclosed |
| US-20170335162-A1 | SALT-TOLERANT, THERMALLY-STABLE RHEOLOGY MODIFIERS | HERCULES LLC | 2017-11-23 | — | — | US | disclosed |
| US-9611416-B2 | Salt-tolerant, thermally-stable rheology modifiers | ISP INVESTMENTS LLC (US) | 2017-04-04 | — | — | US | disclosed |
| US-20130324443-A1 | SALT-TOLERANT, THERMALLY-STABLE RHEOLOGY MODIFIERS | ISP INVESTMENTS INC. (US) | 2013-12-05 | — | — | US | disclosed |
| WO-2013162902-A1 | SYNERGISTIC COMBINATION OF A FLUID LOSS ADDITIVE AND RHEOLOGY MODIFIER | ISP INVESTMENTS INC (US) | 2013-10-31 | — | — | WO | disclosed |
| WO-2013138156-A1 | SYNTHESIS AND APPLICATION OF HIGH PRESSURE HIGH TEMPERATURE FLUID LOSS ADDITIVE AND RHEOLOGY STABILIZER | ISP INVESTMENTS INC. (US) | 2013-09-19 | — | — | WO | disclosed |
| WO-2012061147-A1 | SALT-TOLERANT, THERMALLY-STABLE RHEOLOGY MODIFIERS | ISP INVESTMENTS INC. (US) | 2012-05-10 | — | — | WO | disclosed |
| US-4612392-A | N-substituted acrylamide and methacrylamide derivatives and their preparation | BASF AKTIENGESELLSCHAFT (DE) | 1986-09-16 | — | — | US | disclosed |
| EP-0087714-B1 | N-SUBSTITUTED (METH)-ACRYL AMIDE DERIVATIVES AND THEIR PREPARATION | BASF Aktiengesellschaft (DE) | 1984-12-05 | — | — | EP | disclosed |
| EP-0087714-A1 | N-Substituted (meth)-acryl amide derivatives and their preparation | BASF Aktiengesellschaft (DE) | 1983-09-07 | — | — | EP | disclosed |