Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 4/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PDE2A | O00408 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21327653 | 0.80 | CSF1R (0.54) | CNR1MAOBCNR2APPNPC1 | |
| SCHEMBL24316414 | 0.80 | TLR8 (0.48) | CNR1MAOBCNR2APPNPC1 | |
| SCHEMBL24316413 | 0.79 | APP (0.45) | CNR1MAOBCNR2APPNPC1 | |
| SCHEMBL19461724 | 0.77 | CSF1R (0.46) | CNR1MAOBCNR2APPNPC1 | |
| SCHEMBL31402943 | 0.74 | APP (0.51) | MAOBAPPNPC1POLBRAB9A | |
| SCHEMBL11213165 | 0.74 | MAPK8 (0.39) | — | |
| SCHEMBL22701726 | 0.73 | KDM4E (0.48) | CNR1MAOBMAOACNR2APP | |
| SCHEMBL22925872 | 0.72 | MAOB (0.50) | MAOBMAOAAPPNPC1RAB9A | |
| SCHEMBL29620984 | 0.72 | MAOB (0.50) | MAOBMAOAAPPNPC1RAB9A | |
| SCHEMBL18894310 | 0.72 | MAOB (0.45) | MAOBMAOAAPPNPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022057895-A1 | HETEROAROMATIC COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2022-03-24 | — | — | WO | disclosed |