Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | CSF1R | P07333 | 3/20 | 0.46 |
| ▸ | XDH | P47989 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KIT | P10721 | 1/20 | 0.42 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29620984 | 1.00 | MAOB (0.50) | MAOBMAOACSF1RXDHNPC1 | |
| SCHEMBL18894310 | 0.84 | MAOB (0.45) | MAOBMAOACSF1RXDHNPC1 | |
| SCHEMBL22925707 | 0.82 | CSF1R (0.49) | MAOBCSF1RNPC1RAB9AKIT | |
| SCHEMBL29620947 | 0.82 | CSF1R (0.49) | MAOBCSF1RNPC1RAB9AKIT | |
| SCHEMBL31403188 | 0.81 | MAOB (0.63) | MAOBMAOAXDHNPC1RAB9A | |
| SCHEMBL27177208 | 0.81 | MAOB (0.59) | MAOBMAOAXDHFNTAFNTB | |
| SCHEMBL27038643 | 0.78 | ALDH1A1 (0.44) | — | |
| SCHEMBL22323976 | 0.77 | CSF1R (0.44) | MAOBMAOACSF1RNPC1RAB9A | |
| SCHEMBL22969739 | 0.77 | NPC1 (0.46) | MAOBCSF1RNPC1RAB9AAPP | |
| SCHEMBL27107675 | 0.77 | NPC1 (0.46) | MAOBCSF1RNPC1RAB9AAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021012018-A1 | INHIBITOR COMPOUNDS | Cincera Therapeutics Pty Ltd (AU) | 2021-01-28 | — | — | WO | disclosed |