Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 16/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.38 |
| ▸ | MTOR | P42345 | 2/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24316587 | 0.87 | CSF1R (0.44) | CSF1RPIK3CAMTOR | |
| SCHEMBL24316588 | 0.86 | CSF1R (0.44) | CSF1RPIK3CAMTOR | |
| SCHEMBL24316546 | 0.80 | CSF1R (0.42) | CSF1R | |
| SCHEMBL24316426 | 0.79 | CSF1R (0.46) | CSF1R | |
| SCHEMBL24316440 | 0.79 | CSF1R (0.38) | CSF1RPIK3CAMTOR | |
| SCHEMBL24316446 | 0.76 | CSF1R (0.42) | CSF1RPIK3CAMTOR | |
| SCHEMBL24316443 | 0.76 | CSF1R (0.59) | CSF1R | |
| SCHEMBL24316434 | 0.76 | CSF1R (0.53) | CSF1RPIK3CAMTORGRM5 | |
| SCHEMBL24316661 | 0.75 | CSF1R (0.52) | CSF1RPIK3CAMTORNTRK1 | |
| SCHEMBL24316982 | 0.75 | CSF1R (0.48) | CSF1RPIK3CAMTORGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022057895-A1 | HETEROAROMATIC COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2022-03-24 | — | — | WO | disclosed |