Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 4/20 | 0.53 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.39 |
| ▸ | MTOR | P42345 | 4/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24316982 | 0.95 | CSF1R (0.48) | CSF1RPIK3CAMTORRXFP1ALKBH1 | |
| SCHEMBL24316814 | 0.93 | CSF1R (0.47) | CSF1RPIK3CAMTORRXFP1GRM5 | |
| SCHEMBL24316983 | 0.93 | CSF1R (0.46) | CSF1RPIK3CAMTORRXFP1ALKBH1 | |
| SCHEMBL24316545 | 0.92 | CSF1R (0.43) | CSF1RPIK3CAMTORRXFP1ALKBH1 | |
| SCHEMBL24316448 | 0.92 | CSF1R (0.45) | CSF1RPIK3CAMTORRXFP1GRM5 | |
| SCHEMBL24316565 | 0.91 | CSF1R (0.44) | CSF1RPIK3CAMTORRXFP1ALKBH1 | |
| SCHEMBL24316661 | 0.91 | CSF1R (0.52) | CSF1RPIK3CAMTORRXFP1ALKBH1 | |
| SCHEMBL24316437 | 0.91 | CSF1R (0.45) | CSF1RPIK3CAMTORRXFP1ALKBH1 | |
| SCHEMBL24316549 | 0.90 | CSF1R (0.43) | CSF1RPIK3CAMTORRXFP1KDM4E | |
| SCHEMBL24316587 | 0.90 | CSF1R (0.44) | CSF1RPIK3CAMTORRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022057895-A1 | HETEROAROMATIC COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2022-03-24 | — | — | WO | disclosed |
| US-9585884-B2 | Pyrimidinone inhibitors of lipoprotein-associated phospholipase A2 | AUSPEX PHARMACEUTICALS, INC. (US) | 2017-03-07 | — | — | US | disclosed |