Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 7/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 10/20 | 0.34 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24316440 | 0.92 | CSF1R (0.38) | CSF1RMCHR1 | |
| SCHEMBL24316587 | 0.92 | CSF1R (0.44) | CSF1RMCHR1 | |
| SCHEMBL24316588 | 0.85 | CSF1R (0.44) | CSF1RMCHR1 | |
| SCHEMBL24316434 | 0.82 | CSF1R (0.53) | CSF1RKDM4E | |
| SCHEMBL24316446 | 0.82 | CSF1R (0.42) | CSF1R | |
| SCHEMBL24316982 | 0.81 | CSF1R (0.48) | CSF1RMCHR1KDM4EGLAGAA | |
| SCHEMBL24316441 | 0.81 | PIK3CA (0.37) | CSF1RMCHR1 | |
| SCHEMBL24316429 | 0.81 | CSF1R (0.40) | CSF1RMCHR1 | |
| SCHEMBL24316814 | 0.80 | CSF1R (0.47) | CSF1RMCHR1KDM4E | |
| SCHEMBL24316983 | 0.79 | CSF1R (0.46) | CSF1RMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4214198-A1 | HETEROAROMATIC COMPOUNDS AND USES THEREOF | Hutchison Medipharma Limited (CN) | 2023-07-26 | — | — | EP | disclosed |
| CN-116323582-A | Heteroaromatic ring compounds and uses thereof | 和记黄埔医药（上海）有限公司 | 2023-06-23 | — | — | CN | disclosed |
| WO-2022057895-A1 | HETEROAROMATIC COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2022-03-24 | — | — | WO | disclosed |
| WO-2022057895-A1 | HETEROAROMATIC COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2022-03-24 | — | — | WO | disclosed |