SCHEMBL24317286 — predicted protein targets

Predicted protein targets (top 15)

	gene	UniProt	supporting neighbours	confidence
▸	CYP1A2	P05177	2/20	0.41

▸	ACHE	P22303	1/20	0.39

▸	ADH1A	P07327	2/20	0.38

▸	CYP2D6	P10635	1/20	0.38

▸	RORC	P51449	3/20	0.37

▸	DRD2	P14416	2/20	0.37

▸	DRD3	P35462	2/20	0.37

▸	OPRM1	P35372	3/20	0.36

▸	OPRD1	P41143	3/20	0.36

▸	OPRK1	P41145	3/20	0.36

▸	SIGMAR1	Q99720	1/20	0.35

▸	ADH1C	P00326	1/20	0.35

▸	ALOX5	P09917	1/20	0.35

▸	KMT2A	Q03164	1/20	0.35

▸	CRHR1	P34998	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL11886728	0.98	CYP1A2 (0.39)	CYP1A2ACHEADH1ACYP2D6RORC
SCHEMBL16299333	0.93	OPRM1 (0.40)	CYP1A2ACHEADH1ACYP2D6RORC
SCHEMBL26242405	0.91	CYP1A2 (0.44)	CYP1A2ADH1ARORCDRD2DRD3
SCHEMBL10035081	0.89	DRD2 (0.40)	CYP1A2CYP2D6RORCDRD2DRD3
SCHEMBL23718067	0.89	CYP1A2 (0.41)	CYP1A2ADH1ARORCDRD2DRD3
SCHEMBL16256932	0.88	CYP1A2 (0.48)	CYP1A2ACHECYP2D6SIGMAR1
SCHEMBL16559079	0.86	CYP1A2 (0.42)	CYP1A2ACHEADH1ACYP2D6OPRM1
SCHEMBL12018411	0.86	CYP1A2 (0.42)	CYP1A2ACHEADH1ACYP2D6OPRM1
SCHEMBL20900599	0.86	CYP1A2 (0.42)	CYP1A2ACHEADH1ACYP2D6OPRM1
SCHEMBL26714515	0.86	CYP1A2 (0.42)	CYP1A2ACHEADH1ACYP2D6OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2022081927-A1	TRICYCLIC COMPOUNDS TO DEGRADE NEOSUBSTRATES FOR MEDICAL THERAPY	C4 THERAPEUTICS, INC. (US)	2022-04-21	—	—	WO	disclosed