Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17346285 | 0.72 | ALDH1A1 (0.39) | MAPTCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL24316161 | 0.71 | ALDH1A1 (0.47) | ALDH1A1CYP1A2CYP2D6CYP3A4SLC2A1 | |
| SCHEMBL7061665 | 0.69 | SLC2A1 (0.56) | MAPTCHRM2CHRM4CHRM1CHRM3 | |
| Hydrochloric Acid SCHEMBL11535429 | 0.68 | SLC2A1 (0.55) | MAPTCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL27010006 | 0.67 | ALDH1A1 (0.48) | ALDH1A1CYP1A2CYP2D6CYP3A4SLC2A1 | |
| SCHEMBL17345997 | 0.65 | DRD2 (0.49) | CHRM2CHRM1ALDH1A1KMT2APOLB | |
| SCHEMBL17346203 | 0.65 | DRD2 (0.46) | ALDH1A1KMT2ACYP1A2CYP2D6CYP3A4 | |
| SCHEMBL11353930 | 0.64 | HPGD (0.51) | MAPTCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL11588327 | 0.63 | ALDH1A1 (0.49) | ALDH1A1KMT2ACYP1A2CYP2D6LMNA | |
| SCHEMBL4270846 | 0.63 | KCNH2 (0.43) | ALDH1A1SLC2A1MTNR1AMTNR1BFDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081927-A1 | TRICYCLIC COMPOUNDS TO DEGRADE NEOSUBSTRATES FOR MEDICAL THERAPY | C4 THERAPEUTICS, INC. (US) | 2022-04-21 | — | — | WO | disclosed |