Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | CDC42BPB | Q9Y5S2 | 1/20 | 0.33 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.31 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23489042 | 0.79 | BCHE (0.31) | — | |
| SCHEMBL23892037 | 0.77 | NCF1 (0.39) | — | |
| SCHEMBL20093659 | 0.77 | CYP2D6 (0.36) | ALDH1A1 | |
| SCHEMBL24498429 | 0.76 | L3MBTL1 (0.39) | ROCK2ROCK1CARM1PRMT6 | |
| SCHEMBL2885366 | 0.76 | CHRM2 (0.38) | ROCK2ROCK1CDC42BPBRPS6KB1AKT1 | |
| SCHEMBL19575592 | 0.76 | CHRM2 (0.38) | ROCK2ROCK1CDC42BPBRPS6KB1AKT1 | |
| SCHEMBL24196665 | 0.73 | RPS6KB1 (0.36) | ROCK2ROCK1CDC42BPBRPS6KB1AKT1 | |
| SCHEMBL13188864 | 0.72 | CARM1 (0.41) | ROCK2ROCK1CDC42BPBRPS6KB1AKT1 | |
| SCHEMBL23133622 | 0.71 | HRH4 (0.35) | — | |
| SCHEMBL23132328 | 0.71 | HRH4 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081927-A1 | TRICYCLIC COMPOUNDS TO DEGRADE NEOSUBSTRATES FOR MEDICAL THERAPY | C4 THERAPEUTICS, INC. (US) | 2022-04-21 | — | — | WO | disclosed |