Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 9/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.32 |
| ▸ | TNKS | O95271 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26620767 | 0.77 | GSK3B (0.37) | IDH1DRD2DRD3GSK3B | |
| SCHEMBL31422500 | 0.77 | AKT2 (0.35) | — | |
| SCHEMBL31477276 | 0.77 | AKT2 (0.35) | — | |
| SCHEMBL29332740 | 0.74 | MTNR1A (0.44) | IDH1 | |
| SCHEMBL881106 | 0.74 | MTNR1A (0.44) | IDH1 | |
| SCHEMBL2669660 | 0.74 | DRD2 (0.41) | GRM4IDH1DRD2DRD3TNKS2 | |
| SCHEMBL31213809 | 0.74 | DRD2 (0.32) | IDH1DRD2DRD3GSK3B | |
| SCHEMBL12610368 | 0.74 | MTNR1A (0.44) | IDH1 | |
| SCHEMBL8376129 | 0.74 | DRD2 (0.41) | GRM4IDH1DRD2DRD3TNKS2 | |
| SCHEMBL21281651 | 0.73 | IDH1 (0.39) | SYKGRM4IDH1TNKS2TNKS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081927-A1 | TRICYCLIC COMPOUNDS TO DEGRADE NEOSUBSTRATES FOR MEDICAL THERAPY | C4 THERAPEUTICS, INC. (US) | 2022-04-21 | — | — | WO | disclosed |