Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 4/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12877465 | 0.75 | TGFBR1 (0.42) | ADORA1GAA | |
| SCHEMBL15134752 | 0.75 | NISCH (0.41) | HTT | |
| SCHEMBL4336235 | 0.71 | POLB (0.44) | ADORA1ADORA3ADORA2AGAA | |
| SCHEMBL11325781 | 0.71 | — | — | |
| SCHEMBL6124953 | 0.71 | — | — | |
| SCHEMBL13762102 | 0.71 | — | — | |
| SCHEMBL13668681 | 0.71 | — | — | |
| SCHEMBL3304072 | 0.67 | ADORA3 (0.38) | ADORA1ADORA3ADORA2A | |
| SCHEMBL12899384 | 0.64 | ADORA1 (0.35) | ADORA1ADORA3ADORA2ADDAH1 | |
| SCHEMBL11337622 | 0.64 | ADORA3 (0.31) | ADORA1ADORA3ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220251042-A1 | TOTAL SYNTHESIS OF PIRFENIDONE | Suzhou Fude Zhaofeng Biochemical Technology Co., Ltd (CN) | 2022-08-11 | — | — | US | disclosed |
| WO-2022052391-A1 | METHOD FOR SYNTHESIZING VORTIOXETINE | 苏州富德兆丰生化科技有限公司 | 2022-03-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220251042-A1 | TOTAL SYNTHESIS OF PIRFENIDONE | PIR, CYP2B6, CYP26B1 | ADORA1 3383/4885ADORA3 3294/4885ADORA2A 3452/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.