Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.44 |
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24315862 | 0.86 | ALDH1A1 (0.53) | ALDH1A1MAPTRAB9ASMN1; SMN2KDM4E | |
| SCHEMBL18248923 | 0.73 | CA12 (0.49) | ALDH1A1MAPTKMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL29426248 | 0.69 | ALDH1A1 (0.52) | ALDH1A1RAB9ASMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL17025484 | 0.69 | ALDH1A1 (0.52) | ALDH1A1RAB9ASMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL22468902 | 0.67 | CA12 (0.61) | ALDH1A1MAPTKMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL8107490 | 0.67 | ALDH1A1 (0.77) | ALDH1A1MAPTKMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL16112294 | 0.67 | RAB9A (0.70) | ALDH1A1MAPTKMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL29923588 | 0.67 | ALDH1A1 (0.50) | ALDH1A1MAPTKMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL3633058 | 0.65 | KMT2A (0.64) | ALDH1A1MAPTKMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL21200870 | 0.65 | ALDH1A1 (0.53) | ALDH1A1MAPTKMT2ARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081927-A1 | TRICYCLIC COMPOUNDS TO DEGRADE NEOSUBSTRATES FOR MEDICAL THERAPY | C4 THERAPEUTICS, INC. (US) | 2022-04-21 | — | — | WO | disclosed |