Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRB | P23467 | 14/20 | 0.53 |
| ▸ | CACNA1H | O95180 | 3/20 | 0.36 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.36 |
| ▸ | CACNA1I | Q9P0X4 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23770076 | 0.88 | PTPRB (0.50) | PTPRBCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL24319129 | 0.86 | PTPRB (0.55) | PTPRBCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL19775180 | 0.83 | PTPRB (0.77) | PTPRB | |
| SCHEMBL24767156 | 0.81 | PTPRB (0.51) | PTPRBCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL23769990 | 0.80 | PTPRB (0.56) | PTPRB | |
| SCHEMBL24318149 | 0.79 | PTPRB (0.45) | PTPRBCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL24319135 | 0.79 | PTPRB (0.56) | PTPRBMEN1KMT2ARAB9A | |
| SCHEMBL24767305 | 0.77 | PTPRB (0.49) | PTPRB | |
| SCHEMBL23770161 | 0.76 | PTPRB (0.53) | PTPRB | |
| SCHEMBL24318259 | 0.74 | PTPRB (0.68) | PTPRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3977994-A1 | ACTIVATORS OF TIE-2 FOR USE IN TREATING INTRAOCULAR PRESSURE | Aerpio Pharmaceuticals, Inc. (US) | 2022-04-06 | — | — | EP | disclosed |