Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.38 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20927236 | 0.80 | NCF1 (0.38) | NCF1 | |
| SCHEMBL3436997 | 0.79 | NCF1 (0.52) | NCF1CACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL24319476 | 0.77 | NCF1 (0.50) | NCF1CACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL23173902 | 0.77 | NCF1 (0.54) | NCF1CACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL25571706 | 0.77 | NCF1 (0.54) | NCF1CACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL25666713 | 0.77 | NCF1 (0.42) | NCF1CACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL25666715 | 0.76 | NCF1 (0.38) | NCF1CACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL13815296 | 0.74 | TSHR (0.32) | — | |
| SCHEMBL4401614 | 0.72 | CHRM5 (0.48) | NCF1CACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL24267159 | 0.72 | NCF1 (0.38) | NCF1CACNA2D1CACNA1BCACNB1CACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023239629-A1 | COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THAT DEGRADE CDK2 | Plexium, Inc. (US) | 2023-12-14 | — | — | WO | disclosed |
| WO-2022047145-A1 | RAPIDLY ACCELERATING FIBROSARCOMA PROTEIN DEGRADING COMPOUNDS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. (US) | 2022-03-03 | — | — | WO | disclosed |