Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11991761 | 0.81 | DRD4 (0.30) | — | |
| SCHEMBL683603 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL2773837 | 0.76 | — | — | |
| SCHEMBL24322203 | 0.75 | TSHR (0.30) | TSHR | |
| SCHEMBL7859519 | 0.75 | — | — | |
| SCHEMBL25695115 | 0.74 | ALDH1A1 (0.33) | — | |
| SCHEMBL24319335 | 0.74 | NCF1 (0.38) | — | |
| SCHEMBL22301817 | 0.71 | TSHR (0.32) | TSHR | |
| SCHEMBL684397 | 0.71 | TSHR (0.36) | TSHR | |
| SCHEMBL81189 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8912182-B2 | Viral polymerase inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-12-16 | — | — | US | disclosed |
| US-8476257-B2 | Viral polymerase inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-07-02 | — | — | US | disclosed |
| WO-2009076747-A1 | VIRAL POLYMERASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-06-25 | — | — | WO | disclosed |