Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 1/20 | 0.30 |
| ▸ | SCN4A | P35499 | 1/20 | 0.30 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.30 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.30 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.30 |
| ▸ | SCN11A | Q9UI33 | 1/20 | 0.30 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.30 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22565083 | 1.00 | SCN1A (0.30) | SCN1ASCN4ASCN7AKCNH2SCN5A | |
| SCHEMBL10196619 | 0.88 | SCN1A (0.42) | SCN1ASCN4ASCN7AKCNH2SCN5A | |
| SCHEMBL17285958 | 0.88 | SCN1A (0.42) | SCN1ASCN4ASCN7AKCNH2SCN5A | |
| SCHEMBL22566297 | 0.86 | — | — | |
| SCHEMBL22565133 | 0.86 | — | — | |
| SCHEMBL17286007 | 0.84 | CHRM5 (0.41) | SCN1ASCN4ASCN7AKCNH2SCN5A | |
| SCHEMBL24319344 | 0.82 | NCF1 (0.45) | SCN1ASCN4ASCN7AKCNH2SCN5A | |
| SCHEMBL24319715 | 0.82 | — | — | |
| SCHEMBL22565080 | 0.82 | NCF1 (0.45) | SCN1ASCN4ASCN7AKCNH2SCN5A | |
| SCHEMBL24319906 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022047145-A1 | RAPIDLY ACCELERATING FIBROSARCOMA PROTEIN DEGRADING COMPOUNDS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. (US) | 2022-03-03 | — | — | WO | disclosed |