SCHEMBL24319701

SCHEMBL24319701

CCC(C)(C)CCCCCF

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.36
CPT2 P23786 1/20 0.36
TDP1 Q9NUW8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18937883 0.89
SCHEMBL7863984 0.86 TDP1 (0.43) FFAR1CPT2TDP1
SCHEMBL1836223 0.86 TDP1 (0.43) FFAR1CPT2TDP1
SCHEMBL1834842 0.86 TDP1 (0.43) FFAR1CPT2TDP1
SCHEMBL27160388 0.83 TDP1 (0.40) FFAR1CPT2TDP1
SCHEMBL22268711 0.83 MEN1 (0.32)
SCHEMBL11947283 0.79 DNM1 (0.46) FFAR1CPT2TDP1
SCHEMBL24095398 0.79 FFAR1 (0.36) FFAR1CPT2TDP1
SCHEMBL24444340 0.79 DNM1 (0.46) FFAR1CPT2TDP1
SCHEMBL25998584 0.79 FFAR1 (0.31) FFAR1CPT2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022051596-A1 BICYCLIC-HETEROCYCLE DERIVATIVES AND THEIR USES AS OREXIN-2 RECEPTOR AGONISTS OREXIA THERAPEUTICS LIMITED (GB) 2022-03-10 WO disclosed