Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCP | P55072 | 18/20 | 0.49 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201002 | 0.80 | VCP (0.69) | VCP | |
| SCHEMBL19586892 | 0.72 | VCP (0.61) | VCP | |
| SCHEMBL21141772 | 0.71 | VCP (0.59) | VCP | |
| SCHEMBL27686945 | 0.68 | KDM4E (0.56) | — | |
| SCHEMBL22200951 | 0.67 | VCP (0.54) | VCP | |
| SCHEMBL8911540 | 0.66 | KDM4E (0.54) | — | |
| SCHEMBL22200925 | 0.65 | VCP (0.50) | VCP | |
| SCHEMBL24671758 | 0.65 | HRH3 (0.60) | HRH3 | |
| SCHEMBL30066472 | 0.65 | HRH3 (0.60) | HRH3 | |
| SCHEMBL9534698 | 0.65 | CHRNA7 (0.53) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11773075-B2 | Modulators of p97 AAA ATPase activity | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2023-10-03 | — | — | US | disclosed |
| US-11773075-B2 | Modulators of p97 AAA ATPase activity | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2023-10-03 | — | — | US | disclosed |
| US-20220089565-A1 | MODULATORS OF P97 AAA ATPASE ACTIVITY | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2022-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220089565-A1 | MODULATORS OF P97 AAA ATPASE ACTIVITY | PSMG3, CDC37, AHSA1 | VCP 21/4885KDM1A 2974/4885HRH3 3565/4885 |
| US-11773075-B2 | Modulators of p97 AAA ATPase activity | PSMG3, CDC37, AHSA1 | VCP 21/4885KDM1A 2974/4885HRH3 3565/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.