SCHEMBL24320985

SCHEMBL24320985

O=C(Nc1ccc(/N=N/c2ccc(NC(=O)c3ccc4c(c3)C(=O)NC4=O)cc2)cc1)c1ccc2c(c1)C(=O)NC2=O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 11/20 0.60
MEN1 O00255 7/20 0.60
RXFP1 Q9HBX9 3/20 0.58
CTDSP1 Q9GZU7 2/20 0.58
POLB P06746 1/20 0.53
KDM4E B2RXH2 2/20 0.53
NPC1 O15118 1/20 0.53
LMNA P02545 1/20 0.53
RAB9A P51151 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
NPSR1 Q6W5P4 1/20 0.53
CASP3 P42574 4/20 0.52
MAPT P10636 1/20 0.52
HTT P42858 1/20 0.52
BACE1 P56817 1/20 0.50
ALDH1A1 P00352 1/20 0.49
KLK7 P49862 1/20 0.49
CASP2 P42575 1/20 0.49
CASP7 P55210 1/20 0.49
CASP6 P55212 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24320988 0.85 KDM4E (0.52) KMT2AMEN1CTDSP1KDM4ESMN1; SMN2
SCHEMBL24321046 0.84 KMT2A (0.53) KMT2AMEN1RXFP1CTDSP1POLB
SCHEMBL7915249 0.84 CASP3 (0.63) KMT2AMEN1RXFP1CTDSP1POLB
SCHEMBL24320986 0.83 KMT2A (0.60) KMT2AMEN1RXFP1CTDSP1POLB
SCHEMBL14235295 0.79 CASP3 (0.57) KMT2AMEN1RXFP1CTDSP1POLB
SCHEMBL24321487 0.78 KMT2A (0.46) KMT2AMEN1RXFP1CTDSP1POLB
SCHEMBL24321488 0.78 KMT2A (0.46) KMT2AMEN1RXFP1CTDSP1POLB
SCHEMBL14542298 0.78 KMT2A (0.72) KMT2AMEN1RXFP1CTDSP1POLB
SCHEMBL24320987 0.77 RXFP1 (0.64) KMT2AMEN1RXFP1CTDSP1POLB
SCHEMBL6264004 0.77 KMT2A (0.76) KMT2AMEN1RXFP1CTDSP1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220107576-A1 RESIN COMPOSITION, TONER FOR DEVELOPING ELECTROSTATIC CHARGE IMAGE, IMAGE FORMING METHOD, PHOTOSENSITIVE ADHESIVE, AND OPTICAL SWITCHING MATERIAL Konica Minolta, Inc. (JP) 2022-04-07 US disclosed